Research

GENETICS & CELL BIOLOGY

DETAIL : GENETICS & CELL BIOLOGY

  • Generated novel DNA probes for fingerprinting;
  • Conducted the first study of its kind on genetic polymorphism within Indian human population;
  • Demonstrated for the first time, genetic basis of extinction of endangered species and co-developed molecular markers for identification;
  • Co-identified novel genetic loci, termed as meng, associated exclusively with human meningiomas;
  • Showed, for the first time, the oxidant-dependent mode of action of the baculovirus antiapoptotic p35 gene;
  • Co-discovered the genetic basis of primary congenital glaucoma (PCG), a form of Childhood blindness with a high penetrance, and co-developed a rapid RFLP based diagnosis of PCG which continues to be used at LVPEI, Hyderabad.

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