Conducted the first study of its kind on genetic polymorphism within Indian human population;
Demonstrated for the first time, genetic basis of extinction of endangered species and co-developed molecular markers for identification;
Co-identified novel genetic loci, termed as meng, associated exclusively with human meningiomas;
Showed, for the first time, the oxidant-dependent mode of action of the baculovirus antiapoptotic p35 gene;
Co-discovered the genetic basis of primary congenital glaucoma (PCG), a form of Childhood blindness with a high penetrance, and co-developed a rapid RFLP based diagnosis of PCG which continues to be used at LVPEI, Hyderabad.